Helicobacter Pylori, commonly known as H.pylori and further referred to as H.Pylori is a gram negative bacteria. It generally inhabits various areas of the human stomach and is responsible for chronic low level inflammation of the stomach lining and is the principle factor in development of duodenal,gastric ulcers and stomach cancer.
If H.Pylori infection is untreated for a long time it will lead serious illnesses such as gastroesophageal reflux disease(GERD), peptic ulcers, and cancers of esophagus and stomach.
H.Pylori is a helix shaped bacterium, it is microaerophilic thus making it an organism which needs oxygen but at a lower concentration, for colonising the stomach and surviving the acidity present in the stomach, the bacteria burrows into the mucus close to the epithelial layer. Due to the presence of a flagella the bacteria can move thro the stomach lumen and embed itself in the stomach's mucoid lining.
Treatment for a H.Pylori infection is generally a combined therapy of proton inhibitors such as omerprazole,pantoprazole and antibiotics clarithromycin and amoxicillin.
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