Vibrio Cholerae also known sometimes as kommabacillus, is a comma shaped Gram negative bacteria with a polar flagella. This bacteria causes as the name suggests, Cholera in human beings.
The bacteria is generally infected through contaminated water, most bacteria dont survive the acidity of the stomach, but the bacterias which do survive propel themselves through the thick mucus to reach intestinal walls by growing the flagella, they rotate through the walls to lodge themselves and thrive here. On reaching the intestinal walls they start producing toxic proteins which in turn gives the carrier of the bacteria watery diarrhea.
Treatment of V.Choerae infection is mostly 3 pronged approach, by Oral rehydration therapy, by maintaining electrolyte levels and by the use of antibiotics, such as Doxycycline as firstline and cotrimoxazole, erythromycin, tetracycline, chloramphenicol, and furazolidone.
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